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Algorithmic Thinking in Bioinformatics · Quiz 2 · 4 Aug 2024 · May 2024 term

Question 1: Fill the given blanks to complete the Neighbor-Joining al…

Question 1

+3 marksOne correct option

Fill the given blanks to complete the Neighbor-Joining algorithm.

text
NEIGHBORJOINING(D, n)
if n = 2
T ← the tree consisting of a single edge of length D_{1,2}
return T
D* ← the neighbor-joining matrix constructed from the distance matrix D
find elements i and j such that D*_{i,j} is a minimum non-diagonal element of D*
Δ ← (TOTALDISTANCE_D(i) − TOTALDISTANCE_D(j)) / (n − 2)
limbLength_i ← [ I ]
limbLength_j ← [ II ]
add a new row/column m to D so that D_{k,m} = D_{m,k} = 1/2 (D_{k,i} + D_{k,j} − D_{i,j})
for any k
remove rows i and j from D
remove columns i and j from D
T ← NEIGHBORJOINING(D, n − 1)
add two new limbs (connecting node m with leaves i and j) to the tree T
assign length limbLength_i to LIMB(i)
assign length limbLength_j to LIMB(j)
return T
  1. A
  2. B
  3. C
  4. D
Show answer

Correct answer

  • B

Question 1 of 15 in the IIT Madras BS Algorithmic Thinking in Bioinformatics (Algorithmic Thinking in Bioinformatics) Quiz 2 paper sat on 4 Aug 2024, in the May 2024 term (IIT M DEGREE AN EXAM QDB2 4 Aug 2024). It carries 3 marks.

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