Big Data and Biological Networks Quiz 1: 25 February 2024 (January 2024 term)

1. A

   0.7

2. B

   0.28

3. C

   1.4

4. D

   1.2

1. A

   2.7

2. B

   1.91

3. C

   3.83

4. D

   3.2

1. A

   [0, 1, 1, 1, 0, 0]

2. B

   [0, 1, 0, 0, 1, 0]

3. C

   [2, 3, 4]

4. D

   [1,2, 3, 4]

1. A

   Scale-free degree distribution.

2. B

   Small-world phenomenon.

3. C

   Uniform probability of edges between nodes.

4. D

   Hierarchical modular structure.

1. A

   i-c, ii-c, iii-d iv-a

2. B

   i-b, ii-c, iii-a, iv-a

3. C

   i-c, ii-d, iii-a, iv-b

4. D

   i-b, ii-c, iii-d iv-a

1. A

   Both the assertion and reason are correct, and the reason is a correct explanation of the assertion.

2. B

   Both the assertion and reason are correct, but the reason is not a correct explanation of the assertion.

3. C

   The assertion is correct, but the reason is incorrect.

4. D

   The assertion is incorrect, but the reason is correct.

1. A

   Both the assertion and reason are correct, and the reason is a correct explanation of the assertion.

2. B

   Both the assertion and reason are correct, but the reason is not a correct explanation of the assertion.

3. C

   The assertion is correct, but the reason is incorrect.

4. D

   The assertion is incorrect, but the reason is correct.

1. A

   A - 2, B - 1, C - 4, D - 3

2. B

   A - 4, B - 3, C - 1, D - 2

3. C

   A - 4, B - 2, C - 1, D - 3

4. D

   A - 3, B - 2, C - 4, D - 1

Select all that apply.

1. A

2. B

3. C

4. D

Select all that apply.

1. A

   Only the red node has high betweenness

2. B

   The blue node and the red node have high betweenness

3. C

   The blue node has high betweenness and high degree

4. D

   The red node has a high degree

Select all that apply.

1. A

   A smaller characteristic path length indicates a network is tightly connected.

2. B

   In an Erdös–Rényi G(n ,p) network, there are hub nodes to which new nodes connect with higher probability, as the network grows.

3. C

   The degree distribution of Erdös–Rényi G(n ,p) network follows the Poisson distribution, for large n

4. D

   In a hypergraph, every hyper-edge is a subset of V × V where V is the set of all vertices in the graph.

Select all that apply.

1. A

   The network becomes more disconnected.

2. B

   The network transitions to a fully connected graph.

3. C

   The average degree of the network increases.

4. D

   The diameter of the network increases.

1. A

   Labelled, undirected, unweighted

2. B

   Bipartite, labelled, undirected, unweighted

3. C

   Complete, labelled, unweighted

4. D

   Unlabelled, weighted, undirected

1. A

   Synthesis of a new DNA strand from 5’->3’ using the parental strand as a template.

2. B

   Relieving of DNA supercoiling by formed dues to unwinding of the two strands.

3. C

   Prevents annealing of the parental strands.

4. D

   None of these.

1. A

   Only A

2. B

   Only B

3. C

   Both A and B

4. D

   None of these.

1. A

   Study of protein structures.

2. B

   Examination of DNA sequences.

3. C

   Analysis of gene expression at the RNA level.

4. D

   Investigation of cell morphology.

1. A

   Longer read lengths.

2. B

   Higher accuracy.

3. C

   Higher throughput.

4. D

   Lower cost per base.

1. A

   AUG

2. B

   UGA

3. C

   UAA

4. D

   CCC

Select all that apply.

1. A

   DNA Replication occurs from 5’-> 3’ end.

2. B

   The leading strand is synthesised in a continuous manner.

3. C

   DNA polymerase cannot initiate DNA replication.

4. D

   The lagging strand is synthesised in a continuous manner.

Select all that apply.

1. A

   RNA has Uracil instead of Thymine

2. B

   RNA has a deoxyribose sugar backbone.

3. C

   tRNA is translated to protein

4. D

   RNA is more stable than DNA

Select all that apply.

1. A

   Stop codons signal the beginning of translation.

2. B

   There are three different stop codons in the standard genetic code.

3. C

   Stop codons do not specify any amino acid.

4. D

   Mutations converting a stop codon into a start codon can result in normal protein synthesis.

Select all that apply.

1. A

   Studying evolutionary patterns across different strains and species.

2. B

   Identifying the gene expression patterns in cells.

3. C

   Studying post translational modifications.

4. D

   Identify genetic associations to phenotypic traits.

Select all that apply.

1. A

   To study the gene expression patterns amongst different individuals

2. B

   To catalogue the genetic variations in human populations from different ethnic groups.

3. C

   To identify common and rare variants that affect various phenotypes in human genome.

4. D

   To provide a comprehensive resource for understanding human genetic diversity