Quiz Space

Big Data and Biological Networks · End Term · 13 Apr 2025 · January 2025 term

Question 15: Scientists are studying genetic interactions in yeast by…

Question 15

+2 marksOne or more correct options

Scientists are studying genetic interactions in yeast by creating knockout strains. They observe the following results:
● Single deletion of gene A: viable
● Single deletion of gene B: viable
● Single deletion of gene C: viable
● Single deletion of gene D: viable
● Double deletion of genes A and B: lethal
● Double deletion of genes B and C: viable
● Double deletion of genes C and D: lethal
● Double deletion of genes A and D: viable
Which of the following statements correctly describe synthetic lethal interactions in this system?

Select all that apply.

  1. A

    Genes A and B demonstrate synthetic lethality, suggesting they function in parallel pathways that compensate for each other.

  2. B

    Genes B and C show synthetic lethality, indicating they likely function in the same linear pathway.

  3. C

    Genes C and D show synthetic lethality, suggesting their functions might compensate for each other.

  4. D

    Genes A and D do not show synthetic lethality, proving they have no functional relationship whatsoever.

Show answer

Correct answers

  • A

    Genes A and B demonstrate synthetic lethality, suggesting they function in parallel pathways that compensate for each other.

  • C

    Genes C and D show synthetic lethality, suggesting their functions might compensate for each other.

See the whole paperTake it as a mock test

Question 15 of 44 in the IIT Madras BS Big Data and Biological Networks (Big Data and Biological Networks) End Term paper sat on 13 Apr 2025, in the January 2025 term (IIT M IMPROVEMENT AN EXAM QIM3 13 Apr 2025). It carries 2 marks.

More questions from this paper

  1. Q1The bond between two amino acids is called:
  2. Q2How many codons in the genetic code translate to amino acids?
  3. Q3Which of the following is a key characteristic of post-translational modifications?
  4. Q4Which of the following best describes the fundamental principle behind a Genome-Wide Association Study (GWAS)?
  5. Q5Enumerate the total number of strings that can be generated with 20 words?
  6. Q6Figure question
  7. Q7Figure question
  8. Q8Which of the following is false?
  9. Q9Applications of transcriptomics include:
  10. Q10Which of the following mutations could not affect gene expression?
  11. Q11Which of the following distinguish Next-Generation Sequencing from traditional Sanger sequencing?
  12. Q12Which of the following biological processes involve the DNA:
  13. Q13The number of stuck/blocked reactions in the microbe ‘A’ when grown alone is 42. The number of stuck reactions is reduc…
  14. Q14Figure question
  15. Q16Researchers conducted a network motif analysis on two biological networks (Network α and Network β) and obtained the fo…
  16. Q17NOTE: Enter the exact answer without any extra space in the beginning or at the end.
  17. Q18NOTE: Enter the exact answer without any extra space in the beginning or at the end.
  18. Q19In a Watts-Strogatz small-world network model with n nodes, k initial nearest neighbors per node (k ≪ n), and rewiring …
  19. Q20A data science team is analyzing social network interactions to compare user engagement patterns between weekday and we…
  20. Q21What is the average degree (regardless of the direction) of the 4-mer overlap graph constructed from “CAGATGTAT”?
  21. Q22What is the best global alignment score for the sequences "GTACTG" and "TAGTCTG" with the scoring scheme: matches = +2,…
  22. Q23Elucidate the final sequence that is obtained from the kmers: TATT, TGAT, GATC, ATGT, GTAT, CATG, ATCA, TCAT, TGTA.
  23. Q24Consider the following statements:\ Assertion (A): Dynamic Programming based approach is required to solve the sequence…
  24. Q25Choose the correct option: | Task | Category | |---|---| | Predicting whether a user is a bot in a social network | Rel…
  25. Q26Choose the most appropriate option: | Embedding Method | Learning Paradigm | Feature Matrix | |---|---|---| | (1) DeepW…
  26. Q27Figure question
  27. Q28Figure question
  28. Q29Consider a two-layer neural network with the following architecture: h_1 = W_1 x + b_1 z_1 = \text{ReLU}(h_1) h_2 = W_2…
  29. Q30A two-layer neural network with the 2 features, x_1,\ x_2 is defined below: \begin{aligned} h_1 &= W_1 x + b_1 \ z_1 &=…
  30. Q31A research team studying neural connectivity in the prefrontal cortex has mapped interactions between key neurons invol…
  31. Q32A research team studying neural connectivity in the prefrontal cortex has mapped interactions between key neurons invol…
  32. Q33A research team studying neural connectivity in the prefrontal cortex has mapped interactions between key neurons invol…
  33. Q34In a social network analysis study, researchers are examining friendship connections between users on a new platform. I…
  34. Q35Which of the following concepts are fundamental to understanding and performing sequence alignment?
  35. Q36Which of the following is true about genome assembly?
  36. Q37Which of the following statements about GraphSAGE are true?
  37. Q38Task-specific labels are scarce during the training phase. The pretraining helps to develop a general understanding of …
  38. Q39Figure question
  39. Q40What are the limitations of shallow embeddings?
  40. Q41Which of the following are true for graph filters:
  41. Q42Figure question
  42. Q43What is the primary challenge in applying classical deep neural networks to graph structured data?
  43. Q44What is the primary purpose of introducing a normalization step in a neural network