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Algorithmic Thinking in Bioinformatics · End Term · 1 Sept 2024 · May 2024 term · Set QDB1

Question 5: A mass spectrometer generates the following spectrum \mat…

Question 5

+5 marksOne or more correct options

A mass spectrometer generates the following spectrum Spectrum\mathit{Spectrum} for the peptide "Peptide=\mathit{Peptide} = HEQN".

0 114 126 128 129 137 242 251 266 372 379 380 394 508

The figure given below depicts the mass of all amino acids.

GASPVTCILNDKQEMHFRYW
5771879799101103113113114115128128129131137147156163186

The criteria to trim peptides in the leaderboard based cyclopeptide sequencing algorithm is modified as follows:

"Suppose the algorithm is considering the peptide PP. Let the number of elements in the theoretical spectrum of PP be nn. If SCORE(P,Spectrum)<0.75∗n\text{SCORE}(P, \mathit{Spectrum}) < 0.75 * n, then the peptide is trimmed".

Which of the following peptides will be trimmed?

Select all that apply.

  1. A

    HE

  2. B

    NE

  3. C

    ENQ

  4. D

    EQT

  5. E

    None of these

Show answer

Correct answers

  • C

    ENQ

  • D

    EQT

See the whole paperTake it as a mock test

Question 5 of 16 in the IIT Madras BS Algorithmic Thinking in Bioinformatics (Algorithmic Thinking in Bioinformatics) End Term paper sat on 1 Sept 2024, in the May 2024 term (IIT M DEGREE AN EXAM QDB3 01 Sep 2024). It carries 5 marks.

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